Plasmid DNA Production
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Genovac offers plasmid DNA production at the microgram to gram scale. For difficult to produce plasmids or applications that require heightened purity, we offer process development, including host cell screening and second-step chromatography.
Genovac manufactures plasmid DNA at research grade and enhanced research grade quality levels. Both levels yield high-quality product suited for most applications, such as transient transfection for protein or AAV production. Enhanced research grade manufacturing adds the following process controls, relative to research grade:
We offer a full suite of quality tests for plasmid DNA, available for both research grade and enhanced research grade product. In addition to our standard quality tests, Genovac scientists can develop new tests to meet the unique requirements of your project.
Testing
| TEST | STANDARD QUALITY TESTS | OPTIONAL QUALITY TESTS |
|---|---|---|
| Concentration (UV260) |  | |
| Purity (260/280) | | |
| Identity / topology (AGE) | | |
| Identity (sequence) | |
|
| Endotoxin | |
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| Sterility | |
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| Residual host cell DNA | |
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| Residual host cell RNA | |
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| Residual host cell protein | |